真空泵在制药行业真空干燥中的关键作用与选型建议 The Key Role and Selection Guide of Vacuum Pumps in Pharmaceutical Vacuum Drying

本文详细介绍真空泵在制药行业真空干燥工艺中的作用、原理及选型要点，帮助企业优化生产流程，提升产品质量。由上海上诚泵阀制造有限公司提供技术支持与真空系统解决方案。

This article explains the function, working principle, and selection criteria of vacuum pumps in pharmaceutical vacuum drying, helping enterprises optimize their production process and improve product quality. Technical support and vacuum system solutions are provided by Shanghai Shangcheng Pump & Valve Manufacturing Co., Ltd.

一、真空干燥的原理与作用

1. Principle and Function of Vacuum Drying

在制药生产中，真空干燥是一种关键工艺。通过在低压环境下蒸发水分或溶剂，能有效保护药物中的热敏性成分，防止分解或失活。

In pharmaceutical manufacturing, vacuum drying is a critical process. It removes moisture or solvents under low pressure, effectively protecting heat-sensitive ingredients from decomposition or deactivation.

真空泵在此过程中起到形成和维持低压环境的核心作用，其性能直接决定干燥速度、能耗与最终产品质量。

The vacuum pump plays a vital role in creating and maintaining low pressure; its performance directly affects drying speed, energy consumption, and final product quality.

二、真空泵在制药干燥设备中的应用类型

2. Types of Vacuum Pumps Used in Pharmaceutical Drying Equipment

旋片式真空泵（Rotary Vane Vacuum Pump）：结构紧凑、运行平稳，适用于中小型真空干燥机。

Compact structure and stable operation, ideal for small and medium-sized dryers.

水环式真空泵（Liquid Ring Vacuum Pump）：可处理含水蒸气气体，适用于连续生产。

Handles vapor-laden gases, suitable for continuous industrial processes.

罗茨真空泵（Roots Vacuum Pump）：常与前级泵组合使用，实现高真空度和高抽速。

Often combined with a backing pump to achieve high vacuum and large pumping speed.

无油真空泵（Oil-Free Vacuum Pump）：避免油污染，符合GMP洁净要求。

Prevents oil contamination and meets GMP cleanliness standards.

三、选型要点与系统优化

3. Key Selection Factors and System Optimization

在制药行业选用真空泵时，应重点关注以下要点：

When selecting a vacuum pump for pharmaceutical use, attention should be given to:

真空度与抽速匹配 / Vacuum level and pumping speed：确保与干燥设备腔体容积相匹配。

Ensure compatibility with the chamber volume of the dryer.

介质特性 / Gas composition：若气体含有溶剂蒸汽或腐蚀性成分，应选择耐腐蚀、防爆材质。

Choose corrosion-resistant or explosion-proof materials for solvent or reactive gases.

系统密封与冷凝回收 / System sealing and solvent recovery：良好的密封与回收设计可提高能效。

Proper sealing and condensation recovery improve efficiency and sustainability.

维护与清洁性 / Maintenance and hygiene：制药设备应易清洗、维护周期短。

Equipment should allow easy cleaning and have a short maintenance cycle.

四、上海上诚泵阀的技术优势

4. Technical Advantages of Shanghai Shangcheng Pump Valve

上海上诚泵阀制造有限公司专注于真空泵及真空系统研发与生产，产品包括水环真空泵、旋片真空泵、无油真空泵及多级真空系统。

Shanghai Shangcheng Pump & Valve Manufacturing Co., Ltd. specializes in the R&D and production of vacuum pumps and complete vacuum systems, including liquid ring, rotary vane, oil-free, and multi-stage vacuum pumps.

凭借可靠的抽气性能与优良的防腐设计，上诚真空泵广泛应用于制药、化工、食品、环保等行业，为真空干燥、真空浓缩、冷冻干燥等工艺提供稳定支持。

With reliable suction performance and corrosion-resistant design, Shangcheng vacuum pumps are widely used in pharmaceuticals, chemicals, food, and environmental industries, providing stable vacuum support for drying, concentration, and freeze-drying processes.

结语 / Conclusion

真空泵是制药干燥系统的核心设备，合理选型与稳定运行能显著提升生产效率与药品质量。

As the core component of pharmaceutical drying systems, proper selection and stable operation of vacuum pumps greatly improve efficiency and product quality.

选择专业的真空系统供应商，如上海上诚泵阀制造有限公司，意味着获得高效、节能、可靠的真空解决方案。

Choosing a professional supplier such as Shanghai Shangcheng Pump & Valve Manufacturing Co., Ltd. ensures efficient, energy-saving, and reliable vacuum solutions.